
The Substance
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A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
Her latest, The Substance, starring Demi Moore, Margaret Qualley and Dennis Quaid, is a scathing critique of the misogyny of Hollywood, both external and internalized, that drives women to pursue perfection and beauty – at any cost – through a sci-fi and horror lens. The result is one of the most arresting, devastating and thoroughly disturbing movies of 2024, and one of the best body horror movies in recent history.
‘The Substance’ is an extraordinary, gut-wrenching film which offers a visceral take on ageing and bodily degeneration, in what is a career-best turn from Demi Moore. The film is a passionate, audacious riposte to the Hollywood obsession with ageing and the notion that women over a certain age — here identified as 50 — no longer have currency.